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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: P04406




USC-OGP 2-DE database:  P04406


P04406


General information about the entry
View entry in simple text format
Entry nameG3P2_HUMAN
Primary accession numberP04406
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Glyceraldehyde-3-phosphate dehydrogenase; Short=GAPDH; EC=1.2.1.12; AltName: Full=Peptidyl-cysteine S-nitrosylase GAPDH; EC=2.6.99.-;.
Gene nameName=GAPDH
Synonyms=GAPD
ORFNames=CDABP0047, OK/SW-cl.12
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=8.00; Mw=36142
pI=7.62; Mw=36057
pI=7.84; Mw=36057
pI=7.91; Mw=35973
pI=8.23; Mw=35804
pI=8.14; Mw=35720
pI=8.40; Mw=35553



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.07; Mw=35353
pI=7.94; Mw=35254
pI=7.18; Mw=33988
pI=6.98; Mw=33419
pI=5.41; Mw=33325
pI=7.05; Mw=32952
pI=7.78; Mw=32038

Cross-references
UniProtKB/Swiss-ProtP04406; G3P_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameG3P_HUMAN
Primary accession numberP04406
Secondary accession number(s) E7EUT4 P00354 Q53X65
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on March 15, 2017 (version 222)
Name and origin of the protein
DescriptionRecName: Full=Glyceraldehyde-3-phosphate dehydrogenase; Short=GAPDH; EC=1.2.1.12; AltName: Full=Peptidyl-cysteine S-nitrosylase GAPDH; EC=2.6.99.-;
Gene nameName=GAPDH
Synonyms=GAPD
ORFNames=CDABP0047, OK/SW-cl.12
Encoded onName=GAPDH; Synonyms=GAPD; ORFNames=CDABP0047, OK/SW-cl.12
Keywords3D-structure; Acetylation; ADP-ribosylation; Alternative splicing; Apoptosis; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Glycolysis; Membrane; Methylation; NAD; Nucleus; Oxidation; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; S-nitrosylation; Transferase; Translation regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX01677; CAA25833.1; -; mRNA
EMBLM17851; AAA86283.1; -; mRNA
EMBLM33197; AAA52518.1; -; mRNA
EMBLJ02642; AAA52496.1; -; mRNA
EMBLJ04038; AAA53191.1; -; Genomic_DNA
EMBLX53778; CAA37794.1; -; mRNA
EMBLAF261085; AAF99678.1; -; mRNA
EMBLAY007133; AAG01996.1; -; mRNA
EMBLAB062273; BAB93466.1; -; mRNA
EMBLBT006893; AAP35539.1; -; mRNA
EMBLAY340484; AAP88932.1; -; Genomic_DNA
EMBLCR407671; CAG28599.1; -; mRNA
EMBLAC006064; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471116; EAW88787.1; -; Genomic_DNA
EMBLBC001601; AAH01601.1; -; mRNA
EMBLBC004109; AAH04109.1; -; mRNA
EMBLBC009081; AAH09081.1; -; mRNA
EMBLBC013310; AAH13310.1; -; mRNA
EMBLBC023632; AAH23632.1; -; mRNA
EMBLBC025925; AAH25925.1; -; mRNA
EMBLBC026907; AAH26907.1; -; mRNA
EMBLBC029618; AAH29618.1; -; mRNA
EMBLBC083511; AAH83511.1; -; mRNA
CCDSCCDS58201.1; -. [P04406-2]; .
CCDSCCDS8549.1; -. [P04406-1]; .
PIRA31988; DEHUG3; .
RefSeqNP_001243728.1; NM_001256799.2. [P04406-2]; .
RefSeqNP_001276674.1; NM_001289745.1. [P04406-1]; .
RefSeqNP_001276675.1; NM_001289746.1. [P04406-1]; .
RefSeqNP_002037.2; NM_002046.5. [P04406-1]; .
UniGeneHs.544577; -; .
UniGeneHs.592355; -; .
UniGeneHs.598320; -; .
PDB1U8F; X-ray; 1.75 A; O/P/Q/R=1-335
PDB1ZNQ; X-ray; 2.50 A; O/P/Q/R=1-335
PDB2FEH; Model; -; O/P/Q/R=1-335
PDB3GPD; X-ray; 3.50 A; G/R=2-335
PDB4WNC; X-ray; 1.99 A; A/B/C/D/E/F/G/O=1-335
PDB4WNI; X-ray; 2.30 A; A/B/C/O=1-335
PDBsum1U8F; -; .
PDBsum1ZNQ; -; .
PDBsum2FEH; -; .
PDBsum3GPD; -; .
PDBsum4WNC; -; .
PDBsum4WNI; -; .
ProteinModelPortalP04406; -; .
SMRP04406; -; .
BioGrid108868; 202; .
DIPDIP-32521N; -; .
IntActP04406; 94; .
MINTMINT-1150338; -; .
STRING9606.ENSP00000229239; -; .
BindingDBP04406; -; .
ChEMBLCHEMBL2284; -; .
DrugBankDB07347; 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE; .
DrugBankDB02059; Adenosine-5-Diphosphoribose; .
DrugBankDB00157; NADH; .
DrugBankDB03893; Thionicotinamide-Adenine-Dinucleotide; .
iPTMnetP04406; -; .
PhosphoSitePlusP04406; -; .
SwissPalmP04406; -; .
BioMutaGAPDH; -; .
DMDM120649; -; .
DOSAC-COBS-2DPAGEP04406; -; .
OGPP04406; -; .
REPRODUCTION-2DPAGEIPI00219018; -; .
REPRODUCTION-2DPAGEP04406; -; .
SWISS-2DPAGEP04406; -; .
UCD-2DPAGEP04406; -; .
EPDP04406; -; .
PaxDbP04406; -; .
PeptideAtlasP04406; -; .
PRIDEP04406; -; .
TopDownProteomicsP04406-1; -. [P04406-1]; .
DNASU2597; -; .
EnsemblENST00000229239; ENSP00000229239; ENSG00000111640. [P04406-1]; .
EnsemblENST00000396858; ENSP00000380067; ENSG00000111640. [P04406-2]; .
EnsemblENST00000396859; ENSP00000380068; ENSG00000111640. [P04406-1]; .
EnsemblENST00000396861; ENSP00000380070; ENSG00000111640. [P04406-1]; .
EnsemblENST00000619601; ENSP00000478864; ENSG00000111640. [P04406-2]; .
GeneID2597; -; .
KEGGhsa:2597; -; .
UCSCuc031qfw.3; human. [P04406-1]; .
CTD2597; -; .
DisGeNET2597; -; .
GeneCardsGAPDH; -; .
H-InvDBHIX0000949; -; .
H-InvDBHIX0024996; -; .
HGNCHGNC:4141; GAPDH; .
HPACAB005197; -; .
HPACAB016392; -; .
HPAHPA040067; -; .
HPAHPA061280; -; .
MIM138400; gene; .
neXtProtNX_P04406; -; .
OpenTargetsENSG00000111640; -; .
PharmGKBPA28554; -; .
eggNOGKOG0657; Eukaryota; .
eggNOGCOG0057; LUCA; .
GeneTreeENSGT00760000119172; -; .
HOGENOMHOG000071678; -; .
HOVERGENHBG000227; -; .
InParanoidP04406; -; .
KOK00134; -; .
OMAKWGEVGA; -; .
OrthoDBEOG091G0B1Y; -; .
PhylomeDBP04406; -; .
TreeFamTF300533; -; .
BioCycMetaCyc:HS03433-MONOMER; -; .
BRENDA1.2.1.12; 2681; .
ReactomeR-HSA-70171; Glycolysis; .
ReactomeR-HSA-70263; Gluconeogenesis; .
SABIO-RKP04406; -; .
UniPathwayUPA00109; UER00184; .
ChiTaRSGAPDH; human; .
EvolutionaryTraceP04406; -; .
GeneWikiGlyceraldehyde_3-phosphate_dehydrogenase; -; .
GenomeRNAi2597; -; .
PROPR:P04406; -; .
ProteomesUP000005640; Chromosome 12; .
BgeeENSG00000111640; -; .
CleanExHS_GAPDH; -; .
ExpressionAtlasP04406; baseline and differential; .
GenevisibleP04406; HS; .
GOGO:0005737; C:cytoplasm; ISS:UniProtKB; .
GOGO:0005829; C:cytosol; ISS:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0031012; C:extracellular matrix; IDA:BHF-UCL; .
GOGO:0097452; C:GAIT complex; IDA:UniProtKB; .
GOGO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA; .
GOGO:0030529; C:intracellular ribonucleoprotein complex; IDA:UniProtKB; .
GOGO:0005811; C:lipid particle; IDA:UniProtKB; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB; .
GOGO:0031965; C:nuclear membrane; IDA:HPA; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005886; C:plasma membrane; IDA:HPA; .
GOGO:0031982; C:vesicle; IDA:UniProtKB; .
GOGO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; ISS:UniProtKB; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0008017; F:microtubule binding; ISS:UniProtKB; .
GOGO:0051287; F:NAD binding; IEA:InterPro; .
GOGO:0050661; F:NADP binding; IEA:InterPro; .
GOGO:0035605; F:peptidyl-cysteine S-nitrosylase activity; ISS:UniProtKB; .
GOGO:0061621; P:canonical glycolysis; TAS:Reactome; .
GOGO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB; .
GOGO:0006094; P:gluconeogenesis; TAS:Reactome; .
GOGO:0000226; P:microtubule cytoskeleton organization; ISS:UniProtKB; .
GOGO:0017148; P:negative regulation of translation; IDA:UniProtKB; .
GOGO:0051402; P:neuron apoptotic process; ISS:UniProtKB; .
GOGO:0035606; P:peptidyl-cysteine S-trans-nitrosylation; ISS:UniProtKB; .
GOGO:0050821; P:protein stabilization; ISS:UniProtKB; .
GOGO:0016241; P:regulation of macroautophagy; TAS:ParkinsonsUK-UCL; .
Gene3D3.40.50.720; -; 1; .
InterProIPR020831; GlycerAld/Erythrose_P_DH; .
InterProIPR020830; GlycerAld_3-P_DH_AS; .
InterProIPR020829; GlycerAld_3-P_DH_cat; .
InterProIPR020828; GlycerAld_3-P_DH_NAD(P)-bd; .
InterProIPR006424; Glyceraldehyde-3-P_DH_1; .
InterProIPR016040; NAD(P)-bd_dom; .
PANTHERPTHR10836; PTHR10836; 1; .
PfamPF02800; Gp_dh_C; 1; .
PfamPF00044; Gp_dh_N; 1; .
PIRSFPIRSF000149; GAP_DH; 1; .
PRINTSPR00078; G3PDHDRGNASE; .
SMARTSM00846; Gp_dh_N; 1; .
SUPFAMSSF51735; SSF51735; 1; .
TIGRFAMsTIGR01534; GAPDH-I; 1; .
PROSITEPS00071; GAPDH; 1; .



USC-OGP 2-DE database image


Gateways to other related servers


Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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